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YK-4-279
  【编号】:127218

  【产品名称】:YK-4-279

  【规格】:10MG

  【用途】:

  YK-4-279

  Product Name: YK-4-279
  CAS号:1037184-44-3
  分子式:C17H13Cl2NO4
  分子量:366.2
  贮存: 储存温度-20°C
  可溶性: DMSO ≥100mg/mL
  生化和生理学机理:
  YK-4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1. YK-4-279 inhibits Ewing's sarcoma family tumor (ESFT) cell growth; YK-4-279 induces apoptosis. ES-FLI1 is an oncogenic fusion protein found in Ewing’s sarcoma, a family of undifferentiated tumors that occur throughout the body. The binding of RNA helicase A (RHA) to ES-FLI1 promotes its oncogenic function. YK-4-279 is an inhibitor of protein-protein interactions between ES-FLI1 and RHA.
上一篇:XL-147, ≥98% 下一篇:扎那米韦,≥99%



    
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