GW4064, ≥99%
【编号】:129700 【产品名称】:GW4064, ≥99% 【规格】:5MG 【用途】: GW4064, ≥99%
Product Name: GW4064
别名:Benzoic acid, 3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-
CAS号:278779-30-9
分子式:C28H22Cl3NO4
分子量:542.84
介绍: GW4064
贮存: 储存温度-20°C
可溶性:
DMSO 109 mg/mL
Water <1 mg/mL
Ethanol <1 mg/mL
生化和生理学机理:
GW 4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).GW 4064 displays no activity at other nuclear receptors at concentrations up to 1 μM. GW 4064 improves hyperglycaemia and hyperlipidemia in diabetic db/db mice.
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