类风湿性关节炎血清

  【编号】：NIBSC64/002

  【产品名称】：类风湿性关节炎血清

  【规格】：个

  【价格】：2300元

　　类风湿性关节炎血清

　　编号：NIBSC64/002

　　英文：Rheumatoid Arthritis Serum

　　1. INTENDED USE

　　This Standard is produced from freeze-dried sera from patients with

　　Rheumatoid Arthritis.

　　2. CAUTION

　　This preparation is not for administration to humans or animals in

　　the human food chain.

　　This preparation contains material of human origin. The ampouled

　　material has been tested and found negative for HBsAg, anti-HIV and

　　anti-HCV. New, highly sensitive techniques have now shown this

　　preparation to be positive for HCV RNA by PCR. The preparation

　　should be regarded as potentially hazardous to health. The container and

　　its contents should be used and discarded according to your own

　　laboratory procedures. Such procedures probably will include the wearing

　　of protective gloves and avoiding the generation of aerosols. Care should

　　be exercised in opening the container to avoid cuts.

　　3. UNITAGE

　　100 International Units per ampoule

　　4. CONTENTS

　　Country of origin of biological material: United Kingdom.

　　This Standard is produced from freeze-dried sera from patients with

　　Rheumatoid Arthritis.

　　5. STORAGE

　　Store unopened ampoules at -20oC or below.

　　Please note: because of the inherent stability of lyophilized

　　material, NIBSC may ship these materials at ambient temperature.

　　6. DIRECTIONS FOR OPENING

　　Tap the ampoule gently to collect the material at the bottom (labelled)

　　end. Ensure ampoule is scored all round at the narrow part of the

　　neck, with a diamond or tungsten carbide tipped glass knife file or

　　other suitable implement before attempting to open. Place the

　　ampoule in the ampoule opener, positioning the score at position 'A';

　　shown in the diagram below. Surround the ampoule with cloth or

　　layers of tissue paper. Grip the ampoule and holder in the hand and

　　squeeze at point 'B'. The ampoule will snap open. Take care to avoid

　　cuts and projectile glass fragments that enter eyes. Take care that no

　　material is lost from the ampoule and that no glass falls into the

　　ampoule.

　　Side view of ampoule opening device containing an ampoule

　　positioned ready to open. 'A' is the score mark and 'B' the point of

　　applied pressure.

　　7. USE OF MATERIAL

　　No attempt should be made to weigh out any portion of the freeze-dried

　　material prior to reconstitution.

　　The contents of each ampoule may be reconstituted by the addition of

　　0.2ml of either distilled water or buffered saline and the whole contents of

　　the ampoule should be washed out with buffered saline repeatedly to make

　　a total volume of 4ml. This solution will contain 25 IU per ml.

　　8. STABILITY

　　Reference materials are held at NIBSC within assured, temperaturecontrolled

　　storage facilities. Reference Materials should be stored on

　　receipt as indicated on the label.

　　NIBSC follows the policy of WHO with respect to its reference materials.

　　It is the policy of WHO not to assign an expiry date to their international

　　reference materials. They remain valid with the assigned potency and

　　status until withdrawn or amended.

　　Once reconstituted, diluted or aliquoted, users should determine the

　　stability of the material according to their own method of preparation,

　　storage and use.

　　9. REFERENCES

　　S.G Anderson, M.W Bentzon, V. Houba and P.Krag (1970) International

　　Reference Preparation of Rheumatoid Arthritis Serum, Bull. Wld Hlth Org,

　　42, 311-318.

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